Bioabsorbable extended-release antimicrobial wrap for the prevention of breast tissue expander infections

Mino-Wrap (CITI-101) is a malleable, bio-absorbable film impregnated with minocycline and rifampin. It is a novel therapeutic designed to significantly reduce infections associated with the use of breast tissue expanders (TE) used in patients that elect to undergo reconstructive breast surgery.

Program Highlights

  • Potential to be first and only FDA-approved product to prevent infections associated with post mastectomy breast implants
  • Currently in pre-clinical development
  • Development in partnership with The University of Texas MD Anderson Cancer Center and support from medical thought leaders

How it Works

Mino-Wrap is designed to allow the temporary tissue expander used in breast reconstruction surgeries to be inflated without any restrictions, and to aid in the prevention of infection and biofilm formation on the implant over longer durations than current practice. It is placed over or wrapped around the TE in the surgical pocket as a solid film. It swells and liquefies in situ for a specified period of time to provide extended protection against infection from the most likely pathogens.